Blister pack of vardenafil tablets on a bedside table symbolizing treatment for erectile dysfunction

Vardenafil“: what it is and what your next step should be

Disclaimer: This article is for informational purposes only and does not replace professional medical advice, diagnosis, or treatment. Vardenafil is a prescription medication. Always consult a qualified healthcare provider regarding symptoms, medications, and personal health decisions.

Vardenafil (brand name Levitra® and others) is a prescription medication used to treat erectile dysfunction (ED). It belongs to a class of drugs called PDE5 inhibitors, which also includes sildenafil and tadalafil. If you’re here, you may be experiencing changes in erections, researching treatment options, or wondering whether vardenafil is right for you. This guide walks you through the typical user journey—from first symptoms to clear next steps.

3 typical scenarios

Scenario 1: Difficulty achieving or maintaining an erection

Who/what is experienced: You’ve noticed that erections are weaker than before, difficult to achieve, or not lasting long enough for satisfying sexual activity. This happens repeatedly over weeks or months.

What this might mean: Ongoing erection problems may be erectile dysfunction. ED can be linked to blood flow issues, diabetes, high blood pressure, stress, hormonal imbalances, or medication side effects. Occasional difficulty is common; persistent problems deserve evaluation.

What a doctor usually does:

  • Asks about symptom duration, severity, and lifestyle factors (smoking, alcohol, stress).
  • Reviews medications and medical history (heart disease, diabetes).
  • May order blood tests (glucose, cholesterol, testosterone).
  • Assesses cardiovascular risk before prescribing a PDE5 inhibitor such as vardenafil.

Learn more about possible causes of erectile dysfunction and how they are evaluated.

Scenario 2: You have underlying health conditions (diabetes, hypertension, heart disease)

Who/what is experienced: You have chronic conditions and have started experiencing sexual performance issues. You’re unsure whether it’s safe to use ED medication.

What this might mean: ED is common in men with diabetes and cardiovascular disease due to vascular and nerve changes. However, some heart conditions or medications (especially nitrates) can make vardenafil unsafe.

What a doctor usually does:

  • Reviews heart health and exercise tolerance.
  • Checks for nitrate use (e.g., nitroglycerin), which is a contraindication.
  • Evaluates blood pressure control.
  • Determines whether vardenafil or another treatment is appropriate.

Scenario 3: You tried another ED medication but experienced side effects

Who/what is experienced: You previously used sildenafil (Viagra®) or tadalafil (Cialis®) but had headaches, flushing, nasal congestion, or unsatisfactory results.

What this might mean: Different PDE5 inhibitors vary slightly in onset time, duration, and side-effect profiles. Some people tolerate one better than another. Vardenafil may work differently for you, but suitability depends on your health profile.

What a doctor usually does:

  • Discusses prior medication response and side effects.
  • Considers dose adjustments or alternative PDE5 inhibitors.
  • Explores non-drug options if needed.

See our overview of treatment options for erectile dysfunction for a broader comparison.

Decision tree

  1. If erection problems occur occasionally and during stressful periods only → then consider lifestyle factors (sleep, stress, alcohol) and monitor for a few weeks.
  2. If symptoms persist for more than 3 months → then schedule a primary care or urology appointment.
  3. If you have diabetes, high blood pressure, or heart disease → then consult your doctor before trying any ED medication.
  4. If you take nitrates or have unstable heart disease → then do not use vardenafil; seek medical advice for alternatives.
  5. If you are cleared for PDE5 inhibitors → then discuss whether vardenafil is suitable and how to use it as prescribed by a doctor.

When to seek help urgently (red flags)

  • Chest pain during sexual activity: May signal heart strain—seek emergency care.
  • Sudden vision or hearing loss: Rare but serious potential adverse effects of PDE5 inhibitors.
  • Priapism (erection lasting more than 4 hours): Requires urgent treatment to prevent tissue damage.
  • Severe dizziness or fainting: Could indicate dangerous blood pressure changes.
  • Allergic reaction (swelling, difficulty breathing): Call emergency services.

Approaches to treatment/management (overview)

1. PDE5 inhibitors (e.g., vardenafil)
These medications enhance blood flow to the penis during sexual stimulation. Vardenafil typically works within 30–60 minutes and has a moderate duration of action. It should be used as prescribed by a doctor.

2. Lifestyle modification
Improving cardiovascular health can improve erectile function. Weight loss, smoking cessation, physical activity, and limiting alcohol are key measures. Explore our guide on lifestyle changes that support men’s health.

3. Psychological counseling
Performance anxiety, stress, or relationship issues may contribute to ED. Therapy or sex counseling can be effective alone or combined with medication.

4. Hormonal management
If low testosterone is confirmed, hormone therapy may be considered under specialist supervision.

5. Devices or surgical options
Vacuum erection devices, penile injections, or implants may be options when oral medications are ineffective or contraindicated.

Prevention

Not all cases of erectile dysfunction are preventable, but reducing vascular risk factors significantly lowers the likelihood.

  • Maintain healthy blood pressure and cholesterol levels.
  • Manage blood sugar if you have diabetes.
  • Exercise regularly (aerobic activity supports circulation).
  • Stop smoking.
  • Limit excessive alcohol use.
  • Address stress and mental health early.
Method Who it suits Limitations/risks
Vardenafil (PDE5 inhibitor) Men with ED cleared for sexual activity by a doctor Not safe with nitrates; possible headache, flushing, low blood pressure
Lifestyle changes All men, especially with cardiovascular risk factors Requires long-term commitment; gradual results
Psychological therapy Men with stress, anxiety, or relationship factors May require multiple sessions; depends on engagement
Vacuum devices Men who cannot take oral medications Mechanical discomfort; planning required
Hormone therapy Men with confirmed low testosterone Needs monitoring; not suitable without deficiency

Questions to ask your doctor

  • Is my erectile dysfunction likely physical, psychological, or mixed?
  • Am I healthy enough for sexual activity?
  • Is vardenafil safe given my heart condition or medications?
  • How does vardenafil compare to sildenafil or tadalafil for me?
  • What side effects should I watch for?
  • What should I do if the medication doesn’t work?
  • Can lifestyle changes improve my condition?
  • Do I need blood tests before starting treatment?
  • How often can I safely use this medication?
  • When should I schedule follow-up?

Sources

  • U.S. Food and Drug Administration (FDA) – Drug Safety Communications and prescribing information.
  • American Urological Association (AUA) – Erectile Dysfunction Guidelines.
  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) – Erectile Dysfunction Overview.
  • Mayo Clinic – Erectile dysfunction: Symptoms and causes.
  • European Association of Urology (EAU) – Guidelines on Sexual and Reproductive Health.

Next step: If erection problems are persistent or affecting your quality of life, book a medical appointment. With proper evaluation, treatments like vardenafil—when prescribed appropriately—can be both safe and effective.